video tutorial 5-Iodovanillin preparation from vanillin

Name: video tutorial - 5-Iodovanillin preparation from vanillin
Uploaded: 2025-12-11T09:03:43.827Z
Duration: 4 min 30 s
Description: We then weigh out 7.5 grams of pure vanillin powder. Pure vanillin is available under the RoVanil branded professional bakery suppliers...Prepare 12.6 grams of solid iodine

Goal: synthesize 5-iodovanillin by iodination of vanillin.
Reagents: vanillin, potassium iodide, sodium bicarbonate, iodine; solvent: water.
Process: dissolve KI and bicarbonate in water, suspend vanillin, add iodine gradually to form I3-; stir ~2 hours until color changes (yellow to orange) and a yellow solid forms.
Workup: vacuum filter, wash with dilute sodium thiosulfate solution followed by cold water; dry; seal in calcium chloride to complete drying.
Purification: recrystallize from a boiling 20% ethanol / 80% isopropyl alcohol mixture; yield is nearly quantitative; crystals are pale tan to almost gold.
Product notes: faint vanillin aroma; useful intermediate for 5-hydroxyvanillin and syringaldehyde.